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Mem. Inst. Oswaldo Cruz ; 104(4): 659-661, July 2009. tab
Artigo em Inglês | LILACS | ID: lil-523737

RESUMO

Himatanthus articulatus (Vahl) Woodson is a tree found in the northern Amazon savannahs (common name: sucuba) that is used in local Amerindian medicine. Leaf, bark and branch wood methanol extracts, sequentially obtained hexane, ethyl acetate and methanol extracts and latex were evaluated for antifungal and antibacterial activities against American Type Culture Collection (ATCC) and local clinical strains using the disc diffusion method. Methanol extracts and latex inhibited Candida albicans, leaf methanol extracts inhibited Staphylococcus aureus and Bacillus subtilis and bark methanol extracts inhibited B. subtilis. Active extracts inhibited the ATCC and clinical strains. Polar antifungal and antibacterial principles in latex and extracts are thought to be responsible for the inhibition.


Assuntos
Antibacterianos/farmacologia , Antifúngicos/farmacologia , Apocynaceae/química , Candida albicans/efeitos dos fármacos , Escherichia coli/efeitos dos fármacos , Bacilos Gram-Positivos Formadores de Endosporo/efeitos dos fármacos , Antibacterianos/isolamento & purificação , Antifúngicos/isolamento & purificação , Bacillus subtilis/efeitos dos fármacos , Testes de Sensibilidade a Antimicrobianos por Disco-Difusão , Extratos Vegetais/farmacologia , Staphylococcus aureus/efeitos dos fármacos
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