Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Adicionar filtros








Intervalo de ano
1.
Iranian Journal of Pediatrics. 2014; 24 (2): 173-178
em Inglês | IMEMR | ID: emr-196762

RESUMO

Objective: Appropriate treatment of patients with Type 1 diabetes mellitus [T1DM] is necessary to avoid further complications. This study was performed to compare the efficacy of insulin Glargine and Aspart with NPH insulin and regular insulin regimen in a group of children with T1DM


Methods: Forty patients with T1DM were enrolled in this study. During run-in, all subjects were treated with conventional therapy consisting of twice-daily NPH and thrice-daily regular. Following randomization, 20 subjects received Glargine and Aspart and 20 subjects received NPH and Regular insulin


Findings: Mean HbA1c was 8.8% and 8.6% at first and 8.4% and 8.2% at the end of study for subjects randomized initially to Glargine and Aspart and for those randomized to NPH and Regular, respectively [P>0.05]. Mean fasting blood glucose [FBS] of the subjects randomized initially to Glargine and Aspart was 217+/-101 mg/dL, with no significant difference to 196+/-75 mg/dL for those randomized to NPH and Regular [P=0.48]. This was also true at the end of the study. The difference in total cholesterol and triglyceride between the two groups in the beginning of study and at the end did not show any significance


Conclusion: The current study showed no significant difference in glycemic control [Glycated hemoglobin [HbA1c] and FBS] and lipid profile [total cholesterol and triglyceride] between two regimes

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA