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West Indian med. j ; 36(2): 99-103, June 1987. ilus
Artigo em Inglês | LILACS | ID: lil-70695

RESUMO

The Annatto seed coat extract, which is commonly used in folklore in treating diabetes mellitus, has been investigated for its effects on blood sugar levels in the dog. An alkali-soluble hyperglycaemia-inducing fraction was detected, and detailed studies revealed toxic effects in the pancreas and liver accompanied by hyperglycaemia and apparent tendency to increased insulin levels. The toxicity was diminished by feeding riboflavin. The relevance of this finding points to a possible aetiological role in the development of amlnutrition-related diabetes mellitus and also to the potential toxicity inherent in the widespread use of folklore medicines


Assuntos
Cães , Animais , Extratos Vegetais/toxicidade , Medicina Herbária , Hiperglicemia/induzido quimicamente , Medicina Tradicional , Pâncreas/efeitos dos fármacos , Sementes , Fígado/efeitos dos fármacos
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