RESUMO
Pigmented actinic keratosis (PAK) is an uncommon variant of actinic keratosis that can mimic different pigmented lesions, which may be benign or malignant. The diagnosis of PAK is often challenging because of overlapping features with lentigo maligna melanoma (LMM). Clinically, lesions of both conditions almost look similar; the diagnoses must be established histologically and with the help of immunostaining whenever needed. The distinction between a large PAK and LMM is important because their prognosis and management differ. We present a 75-year-old female with annular brown-to-black-colored maculo-plaque on forehead having clinical suspicious of melanocytic malignancy; which was diagnosed with a PAK on biopsy with help of histopathology and confirmed with Melan A/MART‑1 immunostaining.
RESUMO
Verruciform xanthoma (VX) is a rare benign skin condition, primarily of the oral mucosa that can also affect the skin and genital mucosa. The etiology is not yet completely understood; though its association with conditions of chronic inflammation or trauma, chronic lymphedema, chronic graft versus host disease and CHILD syndrome are mentioned in the literature. Here, we report the case of multiple verruciform xanthomas on the bilateral forearms and upper back of a 25-year-old man in the absence of chronic skin disease or systemic disease and surprisingly, he didn’t have mucosal VX too. Histopathology of the lesion showed nodular dense infiltrate of foamy macrophages in the papillary dermis which stained positive for CD68.