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Rev. Soc. Bras. Med. Trop ; 51(3): 352-356, Apr.-June 2018. tab
Artigo em Inglês | LILACS | ID: biblio-1041467

RESUMO

Abstract INTRODUCTION We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. METHODS: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. RESULTS: Oral lesions, mainly pseudomembranous, were significantly related to higher levels of immunosuppression. Of 45 Candida isolates, 66.7% were C. albicans. Most of the isolates were susceptible to the antifungal drugs tested. CONCLUSIONS: Oral lesions were associated with higher immunosuppression levels. Lower susceptibility to antifungals by non-albicans isolates supports the importance of surveillance studies using susceptibility tests to aid in the treatment.


Assuntos
Humanos , Masculino , Feminino , Adulto , Adulto Jovem , Candida/efeitos dos fármacos , Candidíase Bucal/diagnóstico , Infecções Oportunistas Relacionadas com a AIDS/diagnóstico , Antifúngicos/farmacologia , Brasil , Candida/isolamento & purificação , Candida/classificação , Candidíase Bucal/microbiologia , Resistência Microbiana a Medicamentos , Testes de Sensibilidade Microbiana , Fluconazol/farmacologia , Anfotericina B/farmacologia , Técnicas de Tipagem Micológica , Infecções Oportunistas Relacionadas com a AIDS/microbiologia , Itraconazol/farmacologia , Pessoa de Meia-Idade
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