effect of silver nitrate, chloroformic garlic extract, and normal saline in induction of sclerosing cholangitis in rabbits

To evaluate the effects of 0.5% silver nitrate, 20% chloroformic garlic extract, and 0.9% normal saline in induction of sclerosing cholangitis in the bile ducts of rabbits. During a-6-months period from April to September 2006 in Shiraz University Laboratory Animal Research Center, we selected 3 equal groups of rabbits. We injected 0.5% silver nitrate, 20% chloroformic garlic extract, and 0.9% normal saline into the bile ducts of each group. The animals were euthanized, and autopsied after 4 months and the liver and bile ducts were removed and studied histopathologically. Cholangiography was undertaken to evaluate the presence and extent of any sclerosing cholangitis. Animals showed sclerosing cholangitis in silver nitrate group [7 [58%]], one [8%] in chloroformic garlic extract group and one [7%] in normal saline group. The difference between silver nitrate and chloroformic garlic extract groups were statistically significant and similar results were noticed between chloroformic garlic extract and normal saline groups. Twenty percent of chloroformic garlic extract had fewer complications such as sclerosing cholangitis, compared to other materials

Crush preparation cytologic findings of CNS tumors: a study of 199 cases

Crush preparation cytology technique was used during the operative procedure for the diagnosis of 199 CNS tumors. This technique is simple, easy to perform, rapid, and inexpensive. The cytomorphologic findings were excellent and helped achieve a rapid and correct diagnosis. This technique was used on the tiny, small specimens which were not suitable for frozen sectioning. The results were compared with biopsy reports. The overall diagnostic accuracy by this technique was about 97.7%