1.
Neurol India
;
2008 Jan-Mar; 56(1): 93-4
Artigo
em Inglês
| IMSEAR
| ID: sea-121214
2.
Neurol India
;
2007 Jan-Mar; 55(1): 57-60
Artigo
em Inglês
| IMSEAR
| ID: sea-120183
RESUMO
Pachygyria is a disorder of neuronal migration. We report an Indian family with four siblings with developmental delay, infrequent seizures, normal head size and mild to moderate mental retardation. Two of them had bilaterally symmetrical frontotemporal pachygyria. Dysmorphism and neurological signs were absent in the affected subjects. Affected male and female siblings with normal parents suggests autosomal recessive mode of inheritance. We believe these cases represent a new autosomal recessive disorder of neuronal migration. Other similar cases of lissencephaly are reviewed.