Effect of ventilation on systemic blood flow evaluated by echodopplercardiography

Systemic blood flow (Q) was measured by echodopplercardiography in 5 normal young adult males during apnea, eupnea and tachypnea. Measurements were made in a recumbent posture at 3-min intervals. Tachypnea was attained by doubling the respiratory frequency at eupnea at a constant tidal volume. An open glottis was maintained during apnea at the resting respiratory level. The Q values were positively correlated with the respiratory frequency, decreasing from eupnea to apnea and increasing from eupnea to tachypnea (P<0.05). These data demonstrate that echodopplercardiography, a better qualified tool for this purpose, confirms the positive and progressive effects of ventilation on systemic blood flow, as suggested by previous studies based on diverse technical approaches.

Histoplasmose disseminada associada a tuberculose em pacientes imunodeprimidos. / Disseminated histoplasmosis associated with tuberculosis in immunosuppressed patients

Relata-se o caso de um paciente com mieloma multiplo que desenvolveou tuberculose pulmonar e histoplasmose disseminada. O Histoplasma capsulatum foi cultivado do material obtido por aspiracao transcutanea pulmonar. No estudo pos-mortem, confirmou-se a presenca do fungo em ambos os pulmoes, nos linfonodos mediastinais e, em maior numero, na supra-renal direita