1.
Asian Pacific Journal of Tropical Biomedicine
;
(12): 1900-1905, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-500471
RESUMO
Objective: The plant sphaeranthus amaranthoides Burm.f is used in the district thriunalveli in the treatment of various liver disorders. Methods: in the present study the ethanol extract from sphaeranthus amaranthoides was studied against the D-galactosamine hepatotoxicity. Results: significant hepatoprotective effect was obtained against liver damage induced by the D-galactosamine as evident from changed antioxidant enzymes like CAT, SOD, GPx, GST, GSH, G6PD and GR and a normal architecture of liver and mitochondria compared to toxin controls. Conclusions: the results indicate that ethanol extract of the sphaeranthus amaranthoides could be useful in preventing D-galatosamine induced liver injury.