RESUMO
Choroidal osteoma is an unusual form of intraocular calcification seen in otherwise healthy eyes. It is a benign idiopathic osseous tumor of the choroid, typically seen in young females. Choroidal neovascular membrane (CNVM) is a complication seen in one-third of these patients and carries a poor visual outcome. We report a case of a 25-year-old hyperthyroid female with choroidal osteoma and subfoveal CNVM in her left eye which was successfully treated using low-fluence photodynamic therapy (PDT) with verteporfin followed by a single injection of intravitreal ranibizumab.
Assuntos
Adulto , ANTIBODIES, MONOCLONAL, HUMANIZED ADMINISTRATION & , Neoplasias Ósseas/complicações , Neoplasias Ósseas/diagnóstico , Neoplasias Ósseas/tratamento farmacológico , Neoplasias da Coroide/complicações , Neoplasias da Coroide/diagnóstico , Neoplasias da Coroide/tratamento farmacológico , Neovascularização de Coroide/diagnóstico , Neovascularização de Coroide/tratamento farmacológico , Neovascularização de Coroide/etiologia , Diagnóstico Diferencial , Feminino , Seguimentos , Humanos , Injeções Intravítreas , Microscopia Acústica , Osteoma/complicações , Osteoma/diagnóstico , Osteoma/tratamento farmacológico , Fotoquimioterapia/métodos , Tomografia de Coerência Óptica , Acuidade VisualRESUMO
Angioid streaks also called Knapp striae are small breaks in the Bruch's membrane and have been reported with a host of systemic diseases. Rupture of streaks or development of secondary choroidal neovascular membrane (CNVM) carries a dismal visual prognosis. We report the successful treatment of CNVM secondary to Paget's disease using low fluence photodynamic therapy (PDT) and intravitreal ranibizumab.