Uterine leiomyoma: clinical profile at civil hospital, Ahmedabad.

Introduction: Fibroid is the commonest tumor of the reproductive tract. This study was carried out to observe the frequency of fibroids in relation to age, parity, type and method of diagnosis along with clinical manifestations. Material & Method: The material comprised of 100 specimens of lesions of uterus received from patients admitted in Civil Hospital, Ahmedabad. Among these 37 patients presenting with fibroid uterus were included in the study. All details of the case consisting of age & parity, clinical history, relevant investigations, gross features and microscopic features were noted. Observations: Out of the 100 cases, clinical diagnosis of leiomyoma was made in 30 cases and on confirmatory diagnosis by histopathological analysis leiomyoma was observed in 37 cases. Most cases were found in late reproductive and perimenopausal years (89.19%). Majority was multiparous (81.08%) and 5.41% were nulliparous. Menorrhagia was commonest (40.54%), pain was second common symptom (27.02%). Leiomyomas were multiple in 59.46% and commonest variety was intramural (67.57%). Conclusion: Leiomyomas are found frequently in late reproductive and perimenopausal years. Multiparous patients are found to have fibroids more frequently than nulliparous. Most leiomyoma were intramural. Menorrhagia was the commonest clinical feature observed in leiomyoma cases.

Histological study of adenomatous goitre.

Background & objectives: Multinodular goitre is probably the most common endocrine problem in the world today. Neither a well formulated nor a simple procedure is available for the management of MNG, hence the need for the present study. The aim was to study the various modes of presentation, the distribution with respect to age and sex and the usefulness of histological evaluation. Methods: This was a retrospective study of 100 cases of thyroid lesions during the period of April 2009 to October 2010. Results: Adenomatous goiter was found to be the commonest lesion with a frequency of 52 cases (52%).Most of the patients were female accounting for 90.39%. Most of the cases (53.85%) were noted in 21-40 years age group. Commonest presentation was swelling in front of the neck noted in 98% of cases. Conclusion: Commonest histological observation in the present study was adenomatous goitre in 52%. Majority of the patients were females with a M:F ratio of 1:9.4, with the commonest age group being 31-40 yrs. Almost all patients presented with swelling in front of the neck, with other complaints being that of pain, discomfort, dysphagia, dyspnoea and features of hyperthyroidism.