RESUMO
The level of glucose, uric acid, cholesterol triglycerides and transminase (SGOT and SGPT) and also hematological data of hematocrit and white cell count of 1,542 workers age ranging from 35-53 years who came for physical check up during B.E. 2532 – 2534 were analysed for the groups of smokers, drinkers and smokers together with drinkers. All the three groups have significantly high level of biochemistry substances, hematocrit and white cell count than normal group (p < 0.005) except HDL-Cholesterol which is significantly lower than the normal group (p < 0.005). However, the white cell count of habitual drinkers and cholesterol level in smokers together with drinkers have no significantly different from the normal. We categorie the number of cigarette smoked by both questionnaires and the thiocyanate levels, and found the serum thiocyanate levels correlates with the number of cigarette smoked (p < 0.001).
RESUMO
Phitsanulok is a province situated in the southern part of northern Thailand. Studies of hemoglobinopathies of 2,806 individuals during the period 1988-1990 showed an overall incidence of hemoglobinopathies of 38.89%, with HbE as high as 25% which is the highest incidence of HbE in the North of Thailand. Buddhachinaraj Hospital conducted a maternal screening study on 1,015 pregnant women in 1991 as part of a prevention/control program and found that 22.56% (229 women) had hemoglobinopathies. Of those, 102 (44.54%) individuals (83.33% HbE heterozygotes and 8.82% HbE homozygotes) with their spouses participated in a prenatal diagnosis (PND) counseling program; 100% of the females and 96% of the male were willing to accept PND; 71% of the females and 75.6% of the males had no moral objection in PND.