Associated factors with recurrent wheezing in infants: is there difference between the sexes?

Abstract Objective: Identify associated factors for recurrent wheezing (RW) in male and female infants. Methods: Cross-sectional multicentric study using the standardized questionnaire from the Estudio Internacional sobre Sibilancias en Lactantes (EISL). The questionnaire was applied to parents of 9345 infants aged 12-15 months at the time of immunization/routine visits. Results: One thousand two hundred and sixty-one (13.5%) males and nine hundred sixty-three (10.3%) females have had RW (≥3 episodes), respectively (p10 colds episodes (OR = 3.46; IC 95% 2.35-5.07), air pollution (OR = 1.33; IC 95% 1.12-1.59), molds at home (OR = 1.23; IC 95% 1.03-1.47), Afro-descendants (OR = 1.42; IC 95% 1.20-1.69), bronchopneumonia (OR = 1.41; IC; 1.11-1.78), severe episodes of wheezing in the first year (OR = 1.56; IC 95% 1.29-1.89), treatment with bronchodilators (OR = 1.60; IC 95% 1.22-2,1) and treatment with oral corticosteroids (OR = 1,23; IC 95% 0.99-1,52). Associated factors for RW for females were passive smoking (OR = 1.24; IC 95% 1.01-1,51), parents diagnosed with asthma (OR = 1.32; IC 95% 1,08-1,62), parents with allergic rhinitis (OR = 1.26; IC 95% 1.04-1.53), daycare attendance (OR = 1.48; IC 95% 1.17-1,88), colds in the first 6 months of life (OR = 2.19; IC 95% 1.69-2.82), personal diagnosis of asthma (OR = 1.84; IC 95% 1.39-2.44), emergency room visits (OR = 1.78; IC 95% 1.44-2.21), nighttime symptoms (OR = 2.89; IC 95% 2.34-3.53) and updated immunization (OR = 0.62; IC 95% 0.41-0.96). Conclusion: There are differences in associated factors for RW between genders. Identification of these differences could be useful to the approach and management of RW between boys and girls.

Histiocitose X: relato de um caso / Histiocytosis X: case report

O autor apresenta um caso de uma crianca do sexo feminino, 1 ano e 2 meses de idade, internada em hospital de doencas infecto-contagiosas, no periodo de 17.08.88 a 06.12.89, no Hospital Joao de Barros Barreto, Belem,Para, Brasil. Inicialmente foi diagnosticado e tratdo como tuberculose ganglionar e apos um periodo de 55 dias, reavaliado como Histiocitose X - forma de Lettere-Siwe, tendo sido tratado com vinblastina e prednisona, com bom sucesso terapeutico, estando em remissao ha um ano e oito meses. No estudo do caso clinico encontrou-se febre, queda do estado geral, perda ponderal ate desnutricao, prostacao no leito, dermatite seborreica com petequias localizadas especialmente no tronco e face, hepatomegalia volumosa, esplenomegalia acentuada alcancando a fossa iliaca esquerda, lesoes osteoliticas no cranio, umero, omoplata, coluna vertebral; otite media bilateral; infiltracao pulmonar difusa e acentuada adenomegalia cervical, que levou ao diagnostico de tuberculose ganglionar