Estimation Of Serum Β2-Microglobulin In Oral Precancerous Lesions And Oral Squamous Cell Carcinoma.

Background & objectives:The purpose of this study was to assess the serum levels of β2 microglobulin in oral squamous cell carcinoma and oral leukoplakia and to evaluate the possible role of β2 microglobulin as a biochemical parameter in the diagnosis of oral cancer.Methods: Serum β2 microglobulin levels were evaluated using ELISA in thirty patients with oral squamous cell carcinoma, thirty patients with oral leukoplakia, and thirty age-&sexmatched disease-free controls.Results: It was observed that there was a significant increase in serum β2 microglobulin levels in oral squamous cell carcinoma patients as compared to oral leukoplakia and controls. Progressively higher values were obtained as the cancer advanced clinically with respect to clinical staging, tumor size and nodal status. Although, serum β2 microglobulin levels were increased in oral leukoplakia compared to controls, it was found to be statistically insignificant.Interpretation & conclusion: From these results, it seems that evaluation of serum β2 microglobulin levels may be useful as one of the battery of tests in assessment of oral carcinoma and leukoplakia.

Prevalence Of Hernia Among Fishermen Population In Kutch District, India.

Abstracts: Background & Objective: To assess the Prevalence of hernia among fishermen population in Kutch District, India. Methodology: A descriptive cross-sectional study was conducted among 553 adults living in Kutch District, Gujarat, India, during July to August 2014. Chi-square test was used for comparisons. Confidence level and p-value were set at 95% and 5%, respectively. Results: Lingual hernia had highest prevalence (21.8%) followed by Incsional (15.7) and paraumbelical (13.7%). Hernia of right-direct had 45.9% of prevalence which was highest among all followed by left direct (30.1%) and right-indirect (12.1). Conclusion: The prevalence of hernia among fishermen population was higher than general populations. Early diagnosis, easily accessible health facilities and health education are important to prevent complications.

Recent Advances in Wound Management.

Abstracts: New wound care technologies are being developed at an increasingly rapid pace in recent years. These innovations could significantly reduce the overall costs for treating complex and chronic wounds, while offering greater savings in preventing wounds and their recurrence. The ultimate goal of wound management is the prevention of wounds, or the halting of wound deterioration to achieve more rapid healing. This goal can only be accomplished by intervening with appropriate quality care, in a timely manner. Expenses related to wound care may include surgical and diagnostic procedures, pharmaceuticals, and fees for services provided by physicians and other healthcare professionals. Other costs include the use of medical equipment, the use of devices to provide compression or support for surfaces, wound closing, and the cost of skin care protection products, compression bandages, and changing dressings. Patients need access to the best standard of care to heal their wounds, prevent complications and restore quality of life. This is the goal of healthcare providers and is cost-effective for the health care system.

Effect Of Ptosis Surgery On The Astigmatic Refractive Error In Pediatric Patients In Ahmedabad, India – A Prospective Study.

Abstracts: Background & Objective: To determine the effect of ptosis surgery on the astigmatic refractive error in pediatric patients. Methodology During the period of June 2005 to October 2007, a prospective study of 30 patients was carried out among patients attending department of ophthalmology, vadilal sarabhai hospital Ahmedabad. All eyes were refracted with 2% homatropine under full cycloplegia and were screened on keratometer for objective measurement of corneal curvature. All findings were recorded as per performa and analyzed at completion of the trial. Descriptive statistics were calculated. Level of significance was set at p≤0.05. Results: Developmental ptosis was seen in one eye in 26 patients. Only 4 patients (13.4%) had bilateral involvement. Fifteen patients had severe degree of ptosis (50%). When unilateral it was seen more often affecting left eye. A high incidence of amblyopia was associated with astigmatism in congenital ptosis. Conclusion: Patients with congenital ptosis should have cycloplegic refraction as soon as possible, and long-term postoperative refraction checkup is also recommended.