Serum calcium, magnesium and uric acid in preeclampsia and normal pregnancy.

OBJECTIVE: To compare serum calcium, magnesium and uric acid in mild, severe preeclamptic women and normal pregnant women. STUDY DESIGN: Cross-sectional study. Setting: Section of Obstetrics and Gynecology, Taksin Hospital. MATERIAL AND METHOD: The data was collected from 36 normal pregnant women, 35 mild preeclamptic women and 33 severe preeclamptic women who were admitted in the Section of Obstetrics and Gynecology at Taksin Hospital between April 2006 and June 2007. The blood samples were collected and analyzed for calcium, magnesium and uric acid The data was analyzed using Analysis of Variances (ANOVA). RESULTS: The serum calcium in severe preeclamptic women was significantly lower (8.7 +/- 0.59 mg/dl vs. 8.99 +/- 0.31 mg/dl, p = 0.045; and 9.05 +/- 0.52 mg/dl, p = 0 014) and serum uric acid was significantly higher (7.01 +/- 1.93 mg/dl vs. 5.33 +/- 1.23 mg/dl, p < 0.001 and 5.95 +/- 1.9 mg/dl, p = 0.044) than in normal pregnant women and mild preeclamptic women respectively, but there was no difference between normal and mild preeclamptic women. There was no difference in serum magnesium among normal pregnancy and both groups of preeclampsia. CONCLUSION: Hypocalcemia and hyperuricemia correlated to severe preeclampsia.

Comparative study of serum lipid concentrations in preeclampsia and normal pregnancy.

OBJECTIVE: To compare serum lipids in mild, severe preeclamptic women and normal pregnant women. STUDY DESIGN: Cross-sectional study. SETTING: Section of Obstetrics and Gynecology, Taksin Hospital. MATERIAL AND METHOD: The data was collected from 65 normal pregnant women, 40 mild preeclamptic women, and 48 severe preeclamptic women. The blood samples were collected and analyzed for cholesterol, triglyceride, high-density lipoprotein (HDL), and low-density lipoprotein (LDL). The data was analyzed using Analysis of Variances (ANOVA). RESULTS: There was no significant difference in serum cholesterol, triglyceride, HDL, and LDL between normal, mild, and severe preeclamptic women. CONCLUSION: There was no correlation between serum lipids in normal pregnancy and preeclampsia.

50 grams glucose challenge test for screening of gestational diabetes mellitus in each trimester in potential diabetic pregnancy.

OBJECTIVE: To evaluate the cutoff value of the 50 grams glucose challenge test (GCT) for screening of gestational diabetes mellitus (GDM) in each trimester in potential diabetic pregnancy and to determine the prevalence of GDM. STUDY DESIGN: Retrospective descriptive study (Diagnostic test). SETTING: Section of Obstetrics and Gynecology, Taksin Hospital. SUBJECTS: Two thousand and ten potential diabetic pregnant women who attended the antenatal care clinic at Taksin Hospital between August 2004 and December 2005 were identified and recruited based on risk indicators. MATERIAL AND METHOD: A GCT was performed If GCT was positive, 100 grams oral glucose tolerance test (OGTT) was done to confirm the GDM. All relevant data including demographic information, GCT and OGTT results were collected The receiver operating characteristic (ROC) curve was used to identify the cutoff value of GCT for screening of GDM. MAIN OUTCOME MEASURES: The cutoff value of GCT for screening of GDM in each trimester by using ROC curve. RESULTS: The cutoff values of GCT in 1st, 2nd, 3rd, and all trimesters were 179, 177, 184, and 179 mg/dl respectively The authors recommended 177 mg/dl as the cutoff value of GCT for screening of GDM in potential diabetic pregnancy in each trimester The prevalence of GDM in 1st, 2nd, 3rd, and all trimesters were 14.22, 13.04, 11.96, and 13.2% respectively. CONCLUSION: The threshold of 177 mg/dl was recommended as the cutoff value of GCT for screening of GDM in each trimester in potential diabetic pregnancy. The prevalence was 13.2%.