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Background: In patients with liver cirrhosis, renal function hasimportant prognostic impact along with hepatic function.Hence; we planned the present study to assess renal profile inliver cirrhosis patients.Materials & Methods: A total of 40 liver cirrhosis patients wereincluded in the present study. A total of 40 age and gendermatched healthy controls were also included in the presentstudy as study group. Mean serum creatinine levels and bloodurea levels were assessed using an auto-analyzer.Results: Mean serum creatinine levels of the subjects of thestudy group (38.13 mg/dl) were significantly higher thansubjects of the control group (21.25 mg/dl). Blood urea levelsof the subjects of the study group (1.98 mg/dl) weresignificantly higher than subjects of the control group.Conclusion: Liver cirrhosis is significantly associated withaltered renal profile.
RESUMO
Background: Vitamin D a fat soluble unique micronutrient. Deficiency of vitamin D is widely prevalent in Indian Subcontinent despite wide exposure to sunlight round the year. Vitamin D is considered to be most under evaluated and under treated micronutrient round the world. Elderly persons are more prone to develop Vitamin D deficiency because of risk factors. Methods: This study was done to study the prevalence of vitamin D deficiency in healthy adults for southern Rajasthan and its correlation with gender, dietary habits and habitat (urban or rural residence).We evaluated apparently healthy adults of age more than 50 years presenting to hospital for routine evaluation or as accompanying person with patient between January to July 2015.The serum -25 OH CHOLECALCIFEROL (D2+D3) levels were estimated in all the subjects by COBAS e411 (Hitachi, Roche). Results: The study (Males 121, Females 83), aged 50 – 82 years shows normal level (20-32 nag/ml) in only 26% (53), while 74% (151) had <20ng/ml. Women were more deficient (64%) than males (36%); vegetarians more [93% (140)] than non-vegetarians [7% (11)]; urban more 90% (51/56) than rural 69% (100/148). All those who received supplementation improved clinically and bio chemically. Conclusions: Despite abundant sunshine Vitamin D deficiency prevalence is very high among females, vegetarians and urban subjects, for which presumably conventional female over clothing, strict vegetarianism and urban crowdedness are responsible. Supplementation normalizes Vitamin D deficiency. Therefore, proper food fortification in healthy looking and diseased elderly persons is advised.