RESUMO
WHO recommends ciprofloxacin as the drug of choice for bloody diarrhea. We retrospectively analyzed antibiotic response in 100 children with bloody diarrhea admitted between 2006-2010. Cotrimoxazole (n=55) had higher chance of attaining improved appetite and normal activity in 48h, hospitalization of <3d, blood disappearance in ≤5d and not requiring a second antibiotic compared to others (n=45). Older antimicrobials should be tried in all possible situations.
RESUMO
30 MEDLINE indexed Indian journals publishing clinical trials were identified and their editorial policies on trial registration were assessed. Trial registration number was required in 9 journals (30%).16 journals (53.33%) encouraged adherence to the CONSORT Statement, while 22 (73.33%) mentioned ICMJE Guidelines.
RESUMO
Acute lymphatic leukemia (ALL) is the commonest childhood malignancy in India; most patients have no access to specialized health care. Our experience in treating such children who are unable to avail of facilities at specialized centers is described here. The case records of 79 patients with acute lymphatic leukemia, treated at a Government Medical College in Kerala over 15 years were analyzed. Of the 73 patients who completed treatment, 23 survived (36%) 20 had event-free survival more than 5 years after remission. The utilization of available resources is described. We suggest twinning between specialized centers in India and peripheral hospitals as a means to reach more children.