A new macrocyclic phenolic glycoside from Sorghum vulgare root / 中国中药杂志

Eleven compounds were isolated and purified from Sorghum vulgare root extract, through column chromatography over silica gel, MCI gel, and preparative HPLC. Their structures were established by MS, 1 D NMR and 2 D NMR data as sorgholide A(1), β-sitosterol(2), stigmastero(3), daucosterol(4), 4-methoxycinnamic acid(5), taxiphyllin(6), chlorogenic acid(7), p-hydroxybenzaldehyde(8), succini acid(9), trans-p-hydroxycinnamic acid(10), obtusalin(11). Compounds 4,5 and 9-11 were reported from this species for the first time, and compound 1 is the first 24 ring dimeric double lactonol glycoside formed by reverse polymerization of p-hydroxyphenylacetate glucoside, named sorgholide A.

Chemical constituents from medical and edible plants of Rosa roxburghii / 中国中药杂志

Rosa roxburghii, a kind of the medical and edible plants belonging to the Rosaceae family, is widely distributed in the southwest districts of China, especially Guizhou province. Now, by reason of the extensive bioactivities, the plant is widely used in the field of food, health product, drug, and so on. In the course of our continuing search for the bioactive constituents, thirteen compounds were isolated from R. roxburghii, and their structures were determined on the basis of physicochemical property, spectroscopic data and comparison with the literatures, as 2-oxo pomolic acid(1), 1β-hydroxyeuscaphic acid(2), euscaphic acid(3), arjunic acid(4), tormentic acid(5), kaiiichigeside F1(6), rosamultin(7), arjunetin(8), 2ɑ, 3ɑ, 19ɑ-trihydroxy-olean-12-en-28-oic acid 28-O-β-D-glucopyranoside(9), 2α, 3α, 19α, 24-tetrahydroxyolean-12-en-28-oic-acid 28-O-β-D-glucopyranosyl ester(10), pyrogallic acid (11), daucosterol(12), and 1, 2-decanediol(13). Compounds 9 and 10 were firstly obtained from Rosaceae family, and compounds 1,4,5,9-11,13 were isolated from this plant for the first time.

Chemical constituents from an ethnic drug Dicranopteris pedata / 中国药学杂志

OBJECTIVE: To study the chemical constituents of the ethnic drug Dicranopteris pedata. METHODS: The compounds were isolated and purified by comprehensive application of silica gel and Sephadex LH-20 chromatography, and their structures were identified on the basis of comprehensive analysis of their physical and chemical properties, NMR data and references. RESULTS: Fourteen compounds were isolated and elucidated as quercitrin(1), kaempferol 3-O-α-L-rhamnoside(2), rutin(3), hyperoside(4), kaempferol(5), quercetin(6),2-hydroxy-4-methoxy-2',3'-benzochalcone(7),stigmasterol(8), cycloastragenol(9), shikimic acid(10), protocatechuic acid(ll), gallic acid(12),β-sitosterol(13), and daucosterol(14). CONCLUSION: Compound 1-14 are for the first time isolated from D. pedata.

Chemical constituents from Huperzia leishangensis / 中国药学杂志

OBJECTIVE: To study the chemical constituents in the whole plant of Huperzia leishangensis. METHODS: Compounds were isolated and purified by Prep-TLC, silica gel chromatography, Sephadex LH-20 and preparative high performance liquid chromatography, and their structures were identified on the basis of comprehensive analysis of their physical and chemical properties, NMR data and literatures. RESULTS: Ten compounds were isolated and elucidated as (15R)-12,16-epoxy-11,14-dihydroxy-8, 11, 13-abietatrien-7-one (I), 21-epi-serratenediol-3, 21-acetate (II), serratenediol-3-acetate (III), 21-epi-serratenediol-3-acetate (IV), 21α-hydroxy-serrat-14-en-3β-ol(V), 21β-hydroxy-serrat-14-en-3β-ol(VI), huperzine A (VII), sucrose (VIII), β-sitosterol (IX) and β-daucosterol(X). CONCLUSION: Compound I-X were for the first time isolated from H. leishangensis.