Research on Urine Metabolomics of HIV/AIDS Patients with Spleen-lung Qi-deifciency Based on H-NMR Technique / 世界科学技术-中医药现代化

This study was aimed to explore the characteristics of urine metabolomics among HIV/AIDS patients with spleen-lung qi-deficiency. H-NMR technique was combined with principal component analysis and cluster analysis in the comparison of urine metabolic products among 24 HIV/AIDS cases with spleen-lung qi-deficiency and 20 healthy control cases. The results showed that urine metabolic products of HIV/AIDS patients with spleen-lung qi-deficiency and healthy people by H-NMR technique detection and PLS-DA analysis can classify the outline of urine metabolites. There were about 20 variables in the difference between two groups. The speculated substances contained glycyl-L-leucine, L-valine, α-aminobutyric acid, methyl succinic acid, glycine propionyl, and etc. It was concluded that H-NMR technique was able to classify the outline of urine metabolites between HIV/AIDS cases with spleen-lung qi-deficiency and healthy people. Part of the potential existed characteristic markers contributed to the clinical diagnosis of traditional Chinese medicine (TCM) syndrome differentiation of AIDS. It had certain effect in its quantitative analysis.

Some Thoughts on Present Clinical Research of HIV/AIDS / 世界科学技术-中医药现代化

This paper analyzed the importance and urgency of clinical research of HIV/AIDS and discussed the present research situation and bottleneck of HIV/AIDS clinical research . The application and advantages of Chinese medicine in the clinical research of HIV/AIDS had been listed . And it summarized the Chinese medicine research results on HIV/AIDS management . It also suggested the outlook of Chinese medicine in the HIV/AIDS clinical research .

The TCM handbook of AIDS diagnosis and treatment based on evidence-based medicine / 中华中医药杂志

By employing the methods of literature research and specialist consultation,comprehensively and systematically collected case history at home and abroad on Chinese and western medicine in the treatment of AIDS,by distilling the etiopathogenisis and pathogenesis,the character,the clinical stage,TCM four methods of examination,di erentiation of symptoms,the therapeutical principle and method and the e ective prescription,etc,the paper clari ed the character,pathology,etiology and pathogenesis of AIDS by the evaluation and statistic of qualitative and quantitative analysis of evidence based medicine,grasped the present situation of the treatment of AIDS with Chinese and western medicine in the treatment of AIDS,the rule of syndrome di erentiation and the facticity and application of the clinical e cacy.All these are used to the TCM handbook of AIDS diagnosis and treatment.