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Objective@#To investigate the clinical manifestations, endoscopy, pathological features and highrisk factors of ischemic colitis(IC).@*Methods@#The clinical data of 48 inpatients with IC in the Traditional Chinese Medicine Hospital of Yuhuan from January 2016 to December 2017 were analyzed retrospectively.The risk factors of IC were analyzed by logistic regression.@*Results@#IC patients had chronic diseases such as hypertension, hyperlipidemia and diabetes.Clinical symptoms included abdominal pain and bloody stool.Colonoscopy showed that the lesions of colonic mucosa were distributed regionally, manifested as edema, hemorrhage, erosion and pleomorphic ulcer.In severe cases, stenosis of the lumen could be seen.Pathological findings included necrosis, mucosal edema, hemorrhage, ulcer formation, submucosal hemorrhage and inflammatory cell infiltration.Laboratory examination: leukocyte, serum apolipoprotein B, serum fibrinogen, neutrophil, D-dimer, serum TG and TC were higher than normal levels.Logistic regression results showed that hypertension(OR=4.03, P=0.014), diabetes(OR=2.61, P=0.020), high triglyceride (OR=3.21, P=0.022), atrial fibrillation and other factors(OR=2.50, P=0.017) were closely related to the incidence of IC.@*Conclusion@#The symptoms of IC are not typical.Early diagnosis should be made by colonoscopy.Hypertension, diabetes, hyperlipidemia and atrial fibrillation are risk factors of IC.
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Objective To investigate the clinical manifestations ,endoscopy,pathological features and highrisk factors of ischemic colitis ( IC).Methods The clinical data of 48 inpatients with IC in the Traditional Chinese Medicine Hospital of Yuhuan from January 2016 to December 2017 were analyzed retrospectively.The risk factors of IC were analyzed by logistic regression.Results IC patients had chronic diseases such as hypertension,hyperlipidemia and diabetes.Clinical symptoms included abdominal pain and bloody stool.Colonoscopy showed that the lesions of colonic mucosa were distributed regionally ,manifested as edema,hemorrhage,erosion and pleomorphic ulcer.In severe cases, stenosis of the lumen could be seen.Pathological findings included necrosis,mucosal edema,hemorrhage,ulcer formation, submucosal hemorrhage and inflammatory cell infiltration.Laboratory examination:leukocyte,serum apolipoprotein B, serum fibrinogen,neutrophil,D－dimer,serum TG and TC were higher than normal levels.Logistic regression results showed that hypertension (OR＝4.03,P＝0.014),diabetes(OR＝2.61,P＝0.020),high triglyceride ( OR＝3.21, P＝0.022),atrial fibrillation and other factors (OR＝2.50,P＝0.017) were closely related to the incidence of IC. Conclusion The symptoms of IC are not typical.Early diagnosis should be made by colonoscopy.Hypertension, diabetes,hyperlipidemia and atrial fibrillation are risk factors of IC.
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Objective To explore the effect of Xingnaojing injection on cognitive function recovery in patients with acute cerebral infarction. Methods 100 patients with cerebral infarction who were hospitalized from November 2015 to October 2016 were selected and randomly divided into experimental group and control group, with 50 cases in each group.The patients in the control group were treated with routine treatment of cerebral infarction, including treatment of blood circulation, intravenous drip of mannitol to reduce intracranial pressure, subcutaneous injection of low molecular weight heparin sodium anticoagulant, control of blood pressure and blood glucose to appropriate level, and prevention of venous thrombosis.On the basis of the control group, the experimental group received Xingnaojing injection treatment , according to moderate moderation dose and drip rate.We adjusted the dosage and the drop rate according to the illness.The cognitive function was assessed by using Montreal Cognitive Assessment Scale ( MoCA) and minimum mental state examination (MMSE) at admission and after one month of treatment.Results At one month after treatment, the MoCA score of the experimental group and the control group was (27.44 ±2.97), (25.08 ±0.54) respectively, which was higher than that before treatment, but the experimental group was significantly higher than the control group, the difference was statistically significant ( P<0.05 ) .The MMSE scores of the experimental group and the control group were (21.06 ±1.43), (20.29 ±1.16) respectively, the score did not changed compared with before treatment, and the difference was not statistically significant.Conclusion Xingnaojing injection can improve cognitive impairment in patients with acute cerebral infarction, MoCA is better than MMSE in assessmenting the cerebral infarction patients cognitive situation.
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Objective To explore the clinical efficacy of Toutongning capsule combined with nimodipine in the treatment of 76 patients with primary vascular headache.Methods 76 patients with primary vascular headache were selected as the research subjects.According to the different surgery,the patients were randomly divided into control group (n =38) and observation group (n =38).The control group was given compound Danshen injection,while the observation group was given Toutongning capsule combined with nimodipine.The efficacy,the peak systolic velocity(Vs) and pulsatility index(PI) of each vessel,the time of stopping pain,recurrence rate and adverse reaction were compared between the two groups.Results The total effective rate of the observation group was 94.74％,which was higher than 84.21％ of the control group,the difference was statistically significant (x2 =4.785,P ＜ 0.05).The MCA,ACA,BA,VA value of Vs and PI,the time of stopping pain and recurrence rate in the observation group were better than those in the control group (t =5.385,6.834,7.407,6.651,4.032,5.716,6.203,5.016,4.785,x2 =5.473,all P ＜ 0.05).There were no significant differences between the two groups in PCA value of Vs and PI and adverse reaction(t =0.283,0.037,x2 =0.314,all P ＜ 0.05).Conclusion Toutongning capsule combined with nimodipine in the treatment of primary vascular headache has high application value and significant effect,and it can promote cerebral circulation,blood flow,time of stopping pain and recurrence rate,so it is worthy of clinical popularization and application.