Evaluation of hemocompatibility of a new biopolymer material for bioabsorbable stents used for children with vascular stenosis in vitro / 临床儿科杂志

Objective To evaluate the hemocompatibility of polydioxanone(PDO)bioabsorbable stents.Methods Whole blood clotting time,prothrombin time(PT),activated partial thromboplastin time(APTT),platelet adhesion and hemolysis were used to evaluate the hemocompatibility of PDO bioabsorbable stents,and the results were compared with those of 316L stainless stents which are widely used clinically.Results The anticoagulant property of PDO bioabsorbable stents was similar to that of 316L stainless stents.Both PDO bioabsorbable and 316L stainless stents were not prone to activate blood coagulation factors.Compared with 316L stainless stents,PDO bioabsorbable stents had weaker platelet adhesion and activation.Hemolysis ratios of two groups were less than 5%.Conclusions PDO bioabsorbable stents had good hemocompatibility in vitro.

Necrosis and Apoptosis of Cardiocyte Associated in Ventricular Remodeling after Acute Myocardial Infarction(review) / 中国康复理论与实践

@# It was thought that cardiocyte necrosis is the only dead form after acute myocardial infarction. Recent researches have demonstrate that apoptosis and necrosis both are dead forms of cardiocyte, which play important role in the ventricular remodeling after acute myocardial infarction.