The study on interrelation between colonic carcinoma tissue free amino acid and tumor volume / 肠外与肠内营养

Objectives:In order to observe the effect of colonic carcinoma growth on amino acid metabolism. Methods:Levels of tumor tissue 20 free amino acids were measured from 18 patients with colonic carcinoma, and the normal colonic mucosa was used as controls.Reversed Phase High Performance Liquid Chromatography was used for the determination.The correlations between tumor volume and tumor tissue 20 free amino acids were analysed. Results:The contents of colonic carcinoma tissue free glutamine,methionine,arginine,threonine,valine,leucine,phenylalanine,aspargine and serine were significantly increased and the contents of tumor tissue free alanine and tryptophan were significantly decreased when compared with those of normal colon mucosa( P

Clinical significance of acute-phase proteins in the recurrence of gastric cancer / 中国普通外科杂志

Objective To determine the value of acute phase protein in the early diagnosis of recurrence after curative gastric cancer surgery. Methods Acute phase serum protein level was measured before and after the gastric cancer surgery in 120 patients,and was compared with that of the control group. At 1, 3, 6, 9, 12 months after the operation in 87 patients undergoing curative gastric cancer surgery, the levels of acute phase proteins were measured. They were followed up for at least 12 months or until death. Results The levels of serum C reactive protein(CRP), ?1 antitrypsin (?1 AT) and ? acid glycoprotein (? AG) in gastric cancer group were significantly higher than those in the control group (P0.05). In patients who underwent curative gastric cancer surgery in a certain period after the operation, the serum levels of CRP, ?1 AT and ? AG were significantly lower than those before the surgery(P0.05).There were significant difference in CRP,?1 AT and ? AG between the recurrence groups and nonrecurrence group before and after the operation (P