RESUMO
Objective To investigate the effect of atorvastatin on blood lipid and carotid atherosclerosis in patients with hyperlipidemia and cerebral infarction.Methods 98 patients with hyperlipidemia and cerebral in-farction in our hospital from September 2014 to February 2017 were selected and divided into observation group(49 cases)and control group(49 cases)according to the random number table method.The control group was treated with conventional treatment,the observation group was treated with atorvastatin on the ba-sis of the control group.The two groups were treated for 4 weeks.The ADL score,NIHSS score,blood lipid index,carotid IM T and carotid plaque area were compared between the two groups before and after treatment. Results ADL score of the patients in the observation group after treatment higher was than the control group (t=12.7783,P<0.05),NIHSS score was lower than the control group(t=10.941,P<0.05);LDL-C,TC and TG levels after treatment in the observation group were than in the control group(t= 17.239,9.216, 9.800,P<0.05),while the HDL-C level was higher than the control group(t=7.683.P<0.05);the patients in the observation group were treated by carotid artery IM T and carotid plaque area was higher than that of the control group(t=8.919,6.344,P<0.05).Conclusion Atorvastatin can improve hyperlipidemia in pa-tients with cerebral infarction and carotid atherosclerosis,dyslipidemia,has the important research signifi-cance.
RESUMO
Objective To observe the effects of intervention with Simvastatin and Aspirin on carotid artery atherosclerosis(CAA).Methods 120 patients with ischemic cerebrovascular disease and complicated CAA and blood-lipid abnormality were randomly divided into the Simvastatin group,Aspirin group,Simvastatin+ Aspirin group.Each group received corresponding therapy for 6 months.The changes of serum C-reactive protein(CRP) level,blood-lipid level,the carotid artery intimal and media thickness(IMT),the plaque areas before and after treatment and the recurrence rate of cerebrovascular event among the 3 groups were compared.Results Compared with before treatment,the levels of serum CRP were significantly decreased in the 3 groups after treatment(all P