Study on the distributed integration of the HIS and PACS based on CORBA / 生物医学工程学杂志

In medical clinical practice, physicians need to acquire the image and text information of the patient. All the information will be of benefit for physicians to diagnose disease, improve clinical treatment, and do research work. But the information is distributed in different systems, such as medical image information in PACS (Picture Archiving and Communication System) and text records in HIS (Hospital Information System). Today many hospitals are suffering from lack of an integrated system with PACS and HIS. This paper compares PACS with HIS and puts forward a distributed integration method of integrating the PACS and HIS with the prevailing WWW technology. In such a method, the image and the text information are regarded as the common object and the operation whereon as the object operation. Thus the method integrates the PACS with HIS effectively and implements the information resources sharing with the use of web technology.

Study on the natural history of chronic hepatitis B / 中华肝脏病杂志

<p><b>OBJECTIVE</b>By clarifying the natural history of chronic hepatitis B, to evaluate its long-term therapeutic outcome, antiviral drugs efficacy and economic significance.</p><p><b>METHODS</b>A cohort of 183 (mean age of 31.75?.03 years, male/female ratio: 152:31) chronic hepatitis B patients with biopsy-proven and 247 cases of general population as control were followed up by retrospective cohort study. The follow-up time was 11.81?.08 years. This study was focused on long-term clinical outcome including the rate of liver cirrhosis, hepatocellular carcinoma and death, the long-term effect of antiviral drugs and prognostic factors.</p><p><b>RESULTS</b>In chronic hepatitis B patients, 22 (12.02%) developed liver cirrhosis, 12 (6.56%) hepatocellular carcinoma, and 20 (10.93%) died. The cumulative survival probabilities were 97.27%, 91.62%, and 84.47% in 5, 10, and 15 years, respectively. The cumulative probabilities of HCC were 0.00%, 3.19%, and 11.56% in 5, 10, and 15 years, respectively. In 247 control subjects, 6 (2.43%) died, none of them developed cirrhosis or HCC. The rates of death, liver cirrhosis, and HCC in hepatitis B patients were markedly different (P<0.005) compared with controls. The overall mortality of hepatitis B patients was 4.50 folds of the general population. Cox multiple regression analysis showed that old age, severe histological injury, and the positive HBeAg were closely related to liver cirrhosis, while old age, severe histological injury, and male were major factors leading to death. The independent variable of predicted HCC was not found.</p><p><b>CONCLUSIONS</b>The long-term outcome of hepatitis B is poor.</p>