[Variation of troponin T in chronic hemodialysis patients: study about 52 cases]

Patients with severe renal dysfunction have unexplained elevated serum concentrations of cardiac troponin T. Study the frequency of elevated cTnT in hemodialysis patients and investigated whether cTnT is elevated. The patient population consisted of 52 patients on maintenance hemodialysis and 20 healthy subjects. cTnT was measured before and after hemodialysis by using immunoenzymatic method. cTnT were undetectable in 7 cases[<0.01ng/ml] and higher than normal range[up to 0.1ng/ml] in 9 cases. 32 cases have a level of cTnT >0.01 and <0.1ng/ml. In addition, TnTc levels are significantly associated with cardiac dysfunction [p<0.05] and inflammation [p<0.01]. After hemodialysis sessions, TnTc was less than 0.01 ng /1 in 11 patients [21.2%], between 0.01 and 0.1 ng / ml in 32 subjects [61.5%] and greater than 0.1 ng / ml in 9 subjects [17.3%]. In the control group, only 1 subject [5%] had a rate of TnTc between 0.01 and 0.1 ng / ml, whereas it was less than 0.01 ng / ml for all others. We aim a statistically significant positive correlation between the rate of TnTc and heart failure [p <0.05] on the one hand and serum CRP [p <0.01] on the other. The causes of elevated cTnT levels in hemodialysis patients was multiple: cardiac dysfunction, left ventricular dysfunction and inflammation

Cystinic lithiasis: Retrospective study about 25 cases

Cystinuria is a severe form of renal wich is exposed the patient at multiple recurrent. Report and identify the clinical and biochemical caracteristic of cystinuria in Tunisian region. It is a study of 25 cases of cystinuria, concerning at 16 adults and 9 children from 1995 to 2006. Cystinuria is recognized on the basis of spectrophotometric analysis of the stones [24/1586], by study of urinary cristals completed with brands test [5cases] or by the two types of explorations the frequence of cystinuria is 1.5% [25/I586]. 89% stones were renal and 23% were bilateral. The stones have a diameter between 15/30mm and classified type V at morphology. Our data will improve the management based on early diagnosis, regular follow up and respect of dietetic rules