RESUMO
Objectives: to determine the main hemoglobinopathies in order to act for the reduction of the cases of homozygosis and this, by an early prenatal diagnosis
Methods: It is a retrospective study of 37 cases of antenatal diagnosis for hemoglobinopathies during a 5 years period and having detected 8 homozygous fetus
Results: The mean age of the patients was 32 years. 62 per cent of the patients were originating in the North-West of the country. 56.7 per cent of the patients had a marriage between blood relations. A family antecedent of hemoglobinopathy was noted in all of the cases. The age of the pregnancy at the time of the realization of the prenatal diagnosis was 15 weeks of amenorrhoea and 6 days. 75.7 percent of the patients had an amniocentesis and 24.3 per cent a chorionic villus sample. The detected homozygous fetus accounted for 12.6 per cent of the cases for which a medical interruption of pregnancy was practiced
Conclusion: Because of the frequency and gravity of the hemoglobinopathies in our country, of the recommendations to improve quality of tracking are in particular proposed the preferential recourse to the biopsy of the placental villi and, if necessary with the other methods of taking away when the request of the prenatal diagnosis is late