Screening of alangium salvifolium L. for its helicobactericidal activity

Stem and root barks of Alangium salvifolium belonging to the family Alangiaceae were screened for their probable helicobactericidal activity. Aqueous extracts [hot and cold] and solvent extracts [acetone, chloroform and methanol] were screened. Among those, chloroform extract was observed to recover bioactive principles from the plant materials effectively. The MIC and MIC were also observed to be significantly low for human Helicobacter pylori [Hp] isolates. Samples drawn during flowering seasons were better than that of vegetative period. So the plant needs to be pursued as promising candidate in H. pylori eradication