RESUMO
Background: Chronic obstructive pulmonary disease is one of the harmful complication in chemical injuries with sulfur mustard. Corticosteroids, bronchodilators and anti cholinergic are the most common drugs use in this disease in which it isn't definitely treatment but is palliative
Materials and Methods: There were 39 patients suffered by sulfur mustard, non smoker, without history of the use of corticosteroid during last month selected based on the spirometery and American thoracic society criteria and divided into 3 group mild moderate and sever. They underwent intravenous corticosteroid for 8 days and pulmonary function test [PFT] was done before and after treatment
Results: All patients the PFT was increased after treatment FVC and FEV1 increased significantly in contrast the PEF. the results show severity of the obstructon in 33.33% patient was decreased, in 61.4% without change and in 5.12% was increased.31.65 of the patients who had mild obstruction beome better. Also 60% with moderate obstruction and 80% with sever obstruction become as same.so however the more sever obstruction, better recovery
Conclusion: This protocol is a good method to treat the moderate and sever COPD and it recommoned to not treatment the mild ones
RESUMO
Background: Chronic obstructive pulmonary disease is one of the harmful complication in chemical injuries with sulfur mustard. Corticosteroids, bronchodilators and anti cholinergic are the most common drugs use in this disease in which it isn't definitely treatment but is palliative
Materials and Methods: There were 39 patients suffered by sulfur mustard, non smoker, without history of the use of corticosteroid during last month selected based on the spirometery and American thoracic society criteria and divided into 3 group mild moderate and sever. They underwent intravenous corticosteroid for 8 days and pulmonary function test [PFT] was done before and after treatment
Results: All patients the PFT was increased after treatment FVC and FEV1 increased significantly in contrast the PEF. the results show severity of the obstructon in 33.33% patient was decreased, in 61.4% without change and in 5.12% was increased. 31. 65 of the patients who had mild obstruction beome better. Also 60% with moderate obstruction and 80% with sever obstruction become as same.so however the more sever obstruction, better recovery
Conclusion: This protocol is a good method to treat the moderate and sever COPD and it recommoned to not treatment the mild ones