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Arab Journal of Pharmaceutical Sciences. 2004; 2 (9): 25-31
em Árabe | IMEMR | ID: emr-65335

RESUMO

Aminophylline is a bronchodilator used in the management of the reversible airway obstruction due to asthma, chronic bronchitis, and emphysema. The incidence of toxicosis due to the treatment by Aminophylline has a remarkable frequency, and a great importance especially in elderly patients, so that the study has carried out to determine the lethal dose of 50% [LD 50%] of mice after inject them in the peritoneum by increasing doses of Aminophylline. The study has been shown that Aminophylline has an acute toxic effect which appears during the first hour


Assuntos
Masculino , Animais de Laboratório , Aminofilina/toxicidade , Aminofilina/farmacocinética , Camundongos
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