[Association of TNF-alpha promoter G-238A polymorphism and obesity in an Iranian population]

Tumor necrosis factor-alpha [TNF-alpha] is expressed primarily in adiposities, and elevated levels of this cytokine have been linked to obesity and insulin resistance. We, therefore, examined the relationship between this variant and obesity in an Iranian population. Subjects of the Tehran lipid and Glucose Study were classified in two age groups, the under 18 and the above 18; adults were classified in three groups according to their body mass index; BMI<25, 25