Lipid nanoparticles [SLNs and NLCs]: wide range of application from cosmetics to cancer chemotherapy

The present review compiles the applications of lipid nanoparticles mainly solid lipid nanoparticles [SLN] and nanostructured lipid carriers [NLC] for the delivery of pharmaceutical actives. The attempts to overcome the low solubility and bioavailability of some drugs by their incorporation into lipid nanocarriers have been summarized. A special focus of this review is on different routes of administration of SLNs and NLCs which begins from oral route especially for administration of anticancers, parentral route for drug targeting, pulmonary and topical route for administration of antimicrobial, anti-proliferative and anti inflammatory agents, ophthalmic application to finally cosmetic application of lipid nanocarriers