RESUMO
Polyglandular autoimmunity (PGA) type 2 presenting in childhood is extremely rare. We report a case of type 2 PGA who had hypothyroidism, followed by diabetic ketoacidosis and was later diagnosed to have adrenal insufficiency also.
Assuntos
Adolescente , Diabetes Mellitus Tipo 2/complicações , Humanos , Poliendocrinopatias Autoimunes/complicaçõesRESUMO
The etiology of slipped capital femoral epiphysis (SCFE) is unknown, though hormonal as well as mechanical factors have been implicated. We report a case of gigantism who presented with SCFE. This case provides an insight into the genesis of SCFE, which in this case was related to growth hormone excess and sex-hormone deficiency.
Assuntos
Adulto , Constituição Corporal , Epifise Deslocada/etiologia , Cabeça do Fêmur/diagnóstico por imagem , Gigantismo/complicações , Hormônios Esteroides Gonadais/deficiência , Transtornos do Crescimento/complicações , Hormônio do Crescimento/efeitos adversos , Humanos , Fixadores Internos , MasculinoRESUMO
Hyperthyroidism is seen in 3.5-26% of acromegalic subjects, and can occur through TSH-dependent or independent mechanisms. Thyrotoxicosis as the first presenting illness in acromegaly is particularly uncommon, as described in this patient who had both acromegaly and a toxic thyroid adenoma.