1.
Indian Pediatr
;
2008 Feb; 45(2): 148-50
Artigo
em Inglês
| IMSEAR
| ID: sea-14479
RESUMO
Autoimmune Lymphoproliferative syndrome (ALPS) is an inherited disorder manifesting with autoimmune cytopenia, lymphadenopathy and splenomegaly. The differential diagnosis includes infections, autoimmune disorders or malignancies. The disease is characterized by accumulation of double negative (CD3+ CD4- CD8-) T cells (DNT) in the peripheral blood. We describe a case and review the literature.