RESUMO
H.Pylori is an important factor in pathogenesis of numerous diseases including metabolic, gastrointestinal and vascular disorders.The oral cavity has been proposed as a reservoir for Helicobacter pylori that could be responsible for refractoriness of gastric infection to triple therapy (antibiotics, antimicrobials, proton pump inhibitors). Analysis of data suggests that periodontal treatment in combination with systemic therapy could be a promising approach to increasing the therapy’s efficacy and decreasing the risk of infection recurrence. Some authors have given conflicting evidences, to date there has been no clear cut evidence / study which directly correlates H. Pylori infection of periodontal pockets / plaque leading to peptic ulcer, duodenal ulcers and stomach cancers.