Tumours and tumour-like conditions of the para-testicular region--a study of morphological features.

Twenty two patients with tumours or tumour-like conditions of the para-testicular region (PTR) were diagnosed over a 5 year period. Of these, 16 (73%) were benign with only one true neoplasm (papillary cystadenoma). The tumour-like conditions were comprised of 6 cases of adenomatous hyperplasia of epididymis, 4 cases of spermatic granuloma, 2 cases each of spermatocele and nodular-fibrous proliferation and one mesothelial cyst. Three patients with spermatic granuloma gave a history of trauma. No case of adenomatoid tumour was encountered. Six malignant neoplasms were diagnosed (27%) all of which were sarcomas. Five were primary to the PTR and one was a metastatic deposit from a primary leiomyoblastoma of the mesentery. Among the 5 primary sarcomas were 2 cases each of rhabdomyosarcoma and leiomyosarcoma, and 1 case of liposarcoma. The patient with leiomyoblastoma presented first with a measenteric mass which was followed a month later by a rapidly growing mass in the scrotum. Immunohistochemical staining (IHC) and Electron microscopy (EM) were done in this case. Intra-cytoplasmic myofilaments as well as desmosomes were observed. The patients ranged from 14 to 65 years of age and most presented with painless mass in the scrotum. Follow-up was not possible due to practical difficulties.

Persistent müllerian duct syndrome. A report of two cases.

Two cases of persistence of Müllerian duct structures in phenotypic male patients are reported. One of these was aged 16 years and the other 10 months. Both patients had cryptorchidism and inguinal hernia for which they were operated upon. In both patients parts of uterus and fallopian tubes were identified in the hernial sac. Endocrine evaluation was normal. Karyotyping was performed in the second case which revealed a normal male genotype of 46 XY.

Angiolymphoid hyperplasia with eosinophilia (Kimura's disease).

Angiolymphoid hyperplasia with eosinophilia (AHE) is a rare disease entity which usually presents as subcutaneous nodules, sometimes simulating lymphadenopathy or even angiosarcoma. We present here the histopathological aspects of a case which manifested as a subcutaneous forehead nodule, along with the relevant review of literature concerning this rare entity.

Urine culture sensitivity pattern in a private laboratory setup.

During a two year study period, 6163 samples of urine among a total of 10366 miscellaneous samples received for culture, were analysed. Of these 1488 samples (24.15%) showed evidence of infection. In our study, E. Coli was found most frequently (61.40%) followed by Klebsiella (17.1%). The pattern of antibiotic sensitivity was analysed. Ciprofloxacin and Norfloxacin proved to be the most promising among the new generation of antibiotics. Results with Cloxacillin, Colistin and Lincomycin were found to be disappointing. The study serves to analyse the pattern of urinary infection in our setup and also dwells upon the emergence of strains resistant to even the newer antibiotics.