Valvular vegetations? Cardiac amyloidosis is a possibility.

Cardiovascular system is a frequent target for the deposition of amyloid, specially in the primary type. Patients with this condition can present with myocardial dysfunction due to heavy interstitial myocardial deposits. We report a case of primary cardiovascular amyloidosis in a male with sudden cardiac death. The distribution of amyloid was remarkable for exclusive deposition in the pulmonary and systemic arterial adventitia and more strikingly over all valves, specially the mitral valve. These were large enough to simulate vegetations.