Complete genome sequence of community-associated methicillin-resistant staphylococcus aureus (strain USA400-0051), a prototype of the USA400 clone

Staphylococcus aureus subsp. aureus, commonly referred as S. aureus, is an important bacterial pathogen frequently involved in hospital- and community-acquired infections in humans, ranging from skin infections to more severe diseases such as pneumonia, bacteraemia, endocarditis, osteomyelitis, and disseminated infections. Here, we report the complete closed genome sequence of a community-acquired methicillin-resistant S. aureus strain, USA400-0051, which is a prototype of the USA400 clone.

Xylella fastidiosa comparative genomic database is an information resource to explore the annotation, genomic features, and biology of different strains

The Xylella fastidiosa comparative genomic database is a scientific resource with the aim to provide a user-friendly interface for accessing high-quality manually curated genomic annotation and comparative sequence analysis, as well as for identifying and mapping prophage-like elements, a marked feature of Xylella genomes. Here we describe a database and tools for exploring the biology of this important plant pathogen. The hallmarks of this database are the high quality genomic annotation, the functional and comparative genomic analysis and the identification and mapping of prophage-like elements. It is available from web site http://www.xylella.lncc.br.

Factor inhibidor de la migración de leucocitos y degranulación de basófilos en las reacciones de medicamentos / Leukocyte migration-inhibitory factors and basophile degranulation in drug reactions

Se comunican los resultados de un estudio prospectivo realizado en 31 pacientes con historia de reacción adversa a medicamentos con el propósito de descartar fondo alérgico. Se4 comparo la sensibilidad y especificidad de las pruebas del factor inhibidor de la migración de leucocitos y degranulación de basófilos contra las pruebas de exposición . Los resultados se analizaron estadisticamente y se concluyó que las pruebas de laboratorio antes mencionadas tienen poca sensibilidad y especificidad. La prueba de exposición es el método más rápido, útil y sencillo para determinar alergia a medicamentos, teniendo presente que implica mayor riesgo.