RESUMO
Introduction: This study proposes to compare the use of thelow pressure pneumoperitoneum/LPLC (< 9 mm Hg) with theuse of standard pressure pneumoperitoneum/SPLC (14 mmHg) in patients undergoing laparoscopic cholecystectomy ina prospective randomized manner in an attempt to lower theimpact of pneumoperitoneum on human physiology.Method and Materials: The study was carried out with asample size of 50 patients randomised into two groups, onewith 25 patients - SPLC while the other group with 25 patientsLPLC. To compare post-operative pain incidence of shouldertip pain, average operation duration, need of additionalanalgesia post-operatively, duration of hospital stay, change inPulse rate, SBP & DBP in both groups.Result: Incidence and intensity of post-operative pain, postoperative pain referred to the tip of the right shoulder weresignificantly lower in LPLC group compare with SPLC group.The average change in SBP in patients who underwent LPLCwas an increase of 0.83 ± 8.66 mm Hg and in SPLC groupwas an increase of 0.91 ± 14.67 mm Hg. Average change inDBP in patients who underwent LPLC was increase of 1.75± 8.33 mm Hg and in SPLC group was an increase of 2.64 ±8.34 mm Hg and in LPLC group was a decrease of 0.8 ± 12.01beats per minute and in SPLC group was an increase of 1.8± 5.33 beats per minute. The average change in SBP, DBP &heart rate in patients who underwent LPLC & SPLC was notstatistically significant. Average hospital stay for LPLC groupare 1.92 days and for SPLC group its 2.48 days.Conclusion: An uncomplicated gall stone disease can betreated by low pressure laparoscopic cholecystectomy withreasonable safety by an experienced surgeon. It is significantlyadvantageous in terms of post-operative pain, use ofanalgesics, less shoulder tip pain and hospital stay.