RESUMO
Rheumatic chorea is the sole neurologic manifestation of rheumatic fever. It is a debilitating illness lasting for weeks to months. Drugs like diazepam, haloperidol, chlorpromazine take four to six weeks for functional improvement and can cause serious side effects. The authors investigated the role of Vitamin E in reducing rheumatic chorea. A case series of patients of rheumatic chorea were administered Vitamin E in the dose 50 IU daily for fifteen days. The various clinical signs of rheumatic chorea were scored with MAIMS score (Modified Abnormal Involuntary Movement Scale score) which is used for tardive dyskinesia. No other drug for abnormal movements was used. In all the 4 patients who received vitamin E, there was remarkable change by 7th day and almost complete functional improvement by 14th day. Vitamin E is safer than the conventional drugs used for chorea in children. It was found effective in this case series. Its role needs further evaluation by a double-blind randomized controlled trial.
Assuntos
Criança , Coreia/tratamento farmacológico , Esquema de Medicação , Feminino , Humanos , Prognóstico , Febre Reumática/complicações , Resultado do Tratamento , Vitamina E/administração & dosagemRESUMO
Antigen A 60 of Mycobacterium bovis is a cell wall antigen with almost complete cross reactivity with antigen A 60 of Mycobacterium tuberculosis. This antigen was used for the ELISA technique for 100 cases suspected of childhood tuberculosis to evaluate the usefulness of the method in the diagnosis. The positivity rate in pulmonary tuberculosis was 65.1%, in central nervous system tuberculosis 50.0% and in the miscellaneous group 76.4%. The overall positivity was 61.0%, proving the utility of the method for diagnosis.
Assuntos
Adolescente , Antígenos de Bactérias/diagnóstico , Criança , Pré-Escolar , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Lactente , Masculino , Mycobacterium bovis/imunologia , Sensibilidade e Especificidade , Tuberculose/diagnóstico , Tuberculose Pulmonar/diagnósticoRESUMO
Pulmonary Function tests were measured in 261 healthy boys and 254 healthy girls in the age group of 6 to 15 years with standard Benidects Roth type recording spirometer and Wrights Peak Flow Meter. The values of Pulmonary Functions were found to be increased with increase in age. For vital capacity this relation was curvilinear. All values were higher in boys than girls. There was significant positive correlation between pulmonary Function Tests Vital Capacity, (VC), Maximum Voluntary Ventilation (MV), peak Expiratory Flow Rate (PEFR) and anthropometric parameters like height, weight and body surface area. Equations were formed for prediction of V.C., M.V.V. and PEFR values in relation to the height. The values of Pulmonary Functions were lower when compared with Western Standards, but were comparable with different Indian Studies.