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1.
J Cancer Res Ther ; 2008 Oct-Dec; 4(4): 197-9
Artigo em Inglês | IMSEAR | ID: sea-111526

RESUMO

We present a case of a 39-year-old female patient with acute stridor due to a large tumor located at the level of the upper third of her thoracic esophagus. Parathyroid gland tumors are unusual in the differential diagnosis of mediastinal tumors. This tumor was removed via a thoracocervical approach, which offers multiple advantages when used for tumors in this location. The eventual diagnosis on histology was parathyroid adenoma. The patient had no clinical evidence of metabolic abnormalities and her pre- and postoperative calcium and postoperative parathyroid hormone (PTH) levels were within normal limits. This case poses the interesting question of whether identification of elevated PTH levels is an absolute prerequisite for diagnosing parathyroid adenomas. It is an example of a difficult diagnostic and therapeutic problem.


Assuntos
Adenoma , Adulto , Obstrução das Vias Respiratórias , Esôfago/metabolismo , Feminino , Humanos , Neoplasias do Mediastino/metabolismo , Oncologia/métodos , Hormônio Paratireóideo/metabolismo , Neoplasias das Paratireoides/complicações , Tomografia Computadorizada por Raios X/métodos , Resultado do Tratamento
2.
J Postgrad Med ; 2005 Oct-Dec; 51(4): 253-8; discussion 258-9
Artigo em Inglês | IMSEAR | ID: sea-116171

RESUMO

AIM: To obtain information about valved speech and related issues in patients who have undergone total laryngectomy with the help of a new structured questionnaire on voice prosthesis. SETTINGS AND DESIGN: A questionnaire-based pilot study set at a tertiary referral head and neck cancer unit. MATERIALS AND METHODS: Twenty-five patients using voice prostheses, who showed no signs of recurrence after having undergone total laryngectomy were interviewed with the help of a questionnaire that assessed issues such as voice quality, valve maintenance, leakage, quality of life, humidification and hands-free system over the preceding seven days. The data was analyzed using non-parametric tests (Mann-Whitney and Spearman rank). RESULTS: Twenty-five patients (16 males) with a median age of 65 years (IQ range: 59-70 years) had been using the prosthesis for a median of 6 years (IQ range: 5-10 years). The majority of the patients (n=20) were fully informed about their valve size and diameter and most were able to remove and replace their own prosthesis. Fourteen patients (60%) had leakage-related issues. Women were less satisfied with their voice quality as compared to men. Overall, there appeared to be an improvement in quality of life with the use of the voice prosthesis. CONCLUSIONS: The subjects were fairly well informed about their valve and experienced a high level of satisfaction with their voice. This questionnaire serves as a valuable tool for monitoring voice rehabilitation in patients who have undergone laryngectomy.


Assuntos
Idoso , Feminino , Reino Unido , Humanos , Laringectomia , Laringe Artificial , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Projetos Piloto , Estudos Prospectivos , Inquéritos e Questionários , Qualidade da Voz
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