RESUMO
To compare the ESR values by Ves-Matic Easy and Vacuette SRS 20/11 with conventional Westergren method, aiming to validate the automated methods. A cross-sectional study was conducted at Islamabad Diagnostic centre, Islamabad. A total of 108 blood samples were subjected to ESR estimation by manual Westergren method and by automated [Ves-Matic and Vacuette SRS] methods. Results were analyzed on SPSS ver. 17. Results were compared and their correlation was calculated using Pearson correlation coefficient. There is strong positive correlation between Westergren method and Ves-Matic easy methods with Pearson coefficient of 0.97 and highly significant p value of 0.000. Results also show strong positive correlation between Westergren and Vacuette SRS methods with Pearson coefficient of 0.95 and highly significant p value of 0.00. Both automated methods [Ves-Matic Easy and Vacuette SRS] show good correlation to manual Westergren method, and are reliable and suitable for use in high workload clinical laboratory.
RESUMO
Disorders of sex development are among the most complex conditions for which many a time no definitive cause can be found. The birth of a child with ambiguous genitalia represents a big challenge and a multidisciplinary team is required for the diagnosis and management of these patients. We present a case of a 5 year old child whose external genitalia were not well formed and he presented with undescended testes. His ultrasound showed presence of both testes in deep inguinal ring and small left sided uterus. Developmentally and intellectually tire child seemed fine for his age. He was initially brought up as a girl but was upset and felt himself misfit and when he was dressed and made to play with boys his personality changed altogether and he became a lively cheerful child. He was referred for cytogenetic studies and showed 45XO karyotype in 90% metaphases and 46, Xdel[Yq] in 10% metaphases with a small Y chromosome having a significantly deleted q arm.