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Singapore medical journal ; : 87-91, 2015.
Artigo em Inglês | WPRIM | ID: wpr-244779

RESUMO

<p><b>INTRODUCTION</b>There is paucity of local data on the prevalence of blood transmitted infections (BTIs), such as hepatitis B, hepatitis C and human immunodeficiency virus (HIV) infections, among illicit drug users. This study aimed to examine the prevalence of BTIs among substance dependent inpatients and identify the factors associated with BTIs.</p><p><b>METHODS</b>We conducted a retrospective analysis of clinical notes of 170 inpatients with a diagnosis of substance dependence who were admitted at the National Addictions Management Service, Singapore, between 1 June 2009 and 31 May 2010.</p><p><b>RESULTS</b>Majority of the 170 inpatients were male (88.2%) and Chinese (58.2%). The mean age of the patients was 43.1 years, and the main drug of abuse was opioids (86.5%). BTIs were found in 70 (41.2%) inpatients; the prevalence of hepatitis B, hepatitis C and HIV infections was 3.7%, 39.6% and 0%, respectively. Lifetime intravenous drug use, but not needle-sharing, was more common among inpatients who were positive for BTIs (p < 0.01). Logistic regression analysis showed that lifetime intravenous drug use (OR 4.3, 95% CI 1.7- 10.8, p < 0.01) was the only significant predictor of BTIs.</p><p><b>CONCLUSION</b>A large proportion (41.2%) of the substance users seeking help was positive for at least one BTI. Lifetime intravenous drug users were found to be more than four times more likely to have a BTI. Early detection and prevention is essential to improve prognosis.</p>


Assuntos
Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Analgésicos Opioides , Usos Terapêuticos , Infecções por HIV , Sangue , Hepatite B , Sangue , Hepatite C , Sangue , Pacientes Internados , Uso Comum de Agulhas e Seringas , Razão de Chances , Prevalência , Prognóstico , Estudos Retrospectivos , Singapura , Abuso de Substâncias por Via Intravenosa , Sangue , Epidemiologia
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