Prenatal sonographic evaluation of two intracranial teratomas

Prenatal sonographic evaluation is of utmost importance in the detection of congenital anomalies. At the Ultrasound Section of our Radiology service, we incidentally detected fetal intracranial neoplasms in two different patients using non-invasive imaging. Our presumptive diagnosis in both cases was a teratoma, the most common brain tumor in the perinatal period. Subsequent confirmation was provided with pathological samples obtained at autopsy in both patients, revealing immature teratomas. Fetal intracranial tumors are so rare and incredibly, these two unique cases presented in our section within just a few months of one another.

Asymptomatic carcinoma of the endometrium in a patient on adjunctive tamoxifen therapy for carcinoma of the breast

A case report of a 70 years old female, on tamoxifen for over five (5) years after a left mastectomy and with lymphadenectomy and radiotherapy in whom an asymptomatic adenocarcinoma of the endometrium is reported. Review of the literature suggests this association, however, definitive proof that tamoxifen causes cancer of endometrium has not been fully accepted. The best study in this regards is the one from Radiohemmet Oncologic Centre from Stockholm, Sweden. Patients with cancer of the breast that have been over two (2) years on tamoxifen should be screened with endovaginal sonograms for thickness of endometrium, thickness over 9mm and possibly over 5mm should be investigated with hysteroscopy and fractional uterine curetage