Intractable localized inguinal pruritus as a sign of primary hyperparathyroidism

Generalized pruritus is a well-known complication of primary hyperparathyroidism. We present the first case of primary hyperparathyroidism presenting as a severe localized inguinal pruritus. Pruritus completely resolved after subtotal parathyroidectomy suggesting that intractable cutaneous symptoms like pruritus might be added to the current approved indications of parathyroidectomy in primary hyperparathyroidism. This study also discusses the pathophysiology of pruritus in hyperparathyroidism