RESUMO
Abstract Background Bleomycin is a chemotherapeutical drug used to treat several neoplasias, including non-melanoma skin cancer; it is effective in the treatment of basal cell carcinoma (BCC) via intralesional infiltration. Transdermal drug delivery, which includes technologies such as CO2 Laser, Dermapen, Dermaroller and MMP®, delivers the desired medication to treat skin neoplasias and also acts in skin rejuvenation. Objective To treat BCC lesions using bleomycin via MMP®. Methods Ninety-eight BCC lesions in different anatomical areas were treated using MMP® technology to administer and uniformly distribute bleomycin throughout the lesion and in the established safety margin. Results The cure rate after six months was 96.94%; and recurrences were not associated with lesion size and/or depth. Adverse effects were the expected ones. Study limitations The follow-up time was only six months. Conclusion This therapeutic route showed to be promising and effective.
RESUMO
Abstract: BACKGROUND: Extrahepatic manifestations are seen in association with chronic infection by hepatitis B or C virus including cutaneous disorders. The frequency of these findings seems to vary among different places and reports. There is a lack of information about this issue in Brazil. OBJECTIVES: To estimate the prevalence of cutaneous findings affecting HBV or HCV carriers from a reference outpatient unit in Mato Grosso. METHODS: A cross-sectional observational study. RESULTS: 108 patients were studied. 88.9% presented some cutaneous findings but must of them were nonrelated to chronic viral infection. Four patients had cutaneous or autoimmune syndromes that may be HBV or HCV related. CONCLUSION: In our study we found no statistical association between viral hepatitis and skin diseases.
Assuntos
Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Hepatite B Crônica/complicações , Hepatite B Crônica/epidemiologia , Hepatite C Crônica/complicações , Hepatite C Crônica/epidemiologia , Dermatopatias Virais/epidemiologia , Dermatopatias Virais/etiologia , Antivirais/efeitos adversos , Brasil/epidemiologia , Estudos Transversais , Hepatite B Crônica/tratamento farmacológico , Hepatite C Crônica/tratamento farmacológico , Prevalência , Fatores de RiscoRESUMO
Neste trabalho de revisão histórica, atualização, ilustração e apresentação de uma série de acasos de Ceratodermia palmo-plantar, atendidos no serviço de Dermatologia do Hospital Universitário da Universidade Federal de Juiz de Fora, visamos auxiliar na definição, classificação e terapêutica de um tipo especifico de ceratodermia encontrado na prática diária com relativa frequência. Por não ser facilmente diagnosticada , pela dificuldade de classificação, inexperiência ou mesmo falta de conhecimento da existência dessa doença, por vezes esta Ceratodermia é tratada de forma equivocada.