RESUMO
Guizhi decoction come from Typhoid Theory written by Zhang Zhongjing, a famous physician in the Han dynasty. It is called "the leading group of the group" by later doctors. At present, Guizhi decoction is widely used in treatment of many diseases of internal, external, gynecologic and other diseases. This article discusses the clinical application and mechanism of Guizhi decoction in two aspects. This article expounds that Guizhi decoction is widely used in colds, febrile diseases, various perspiration, digestive system diseases and respiratory diseases, Some diseases, such as ear, nose and throat disease, nervous system disease, cardiac autonomic neuropathy, and bone and joint disease. The mechanism of Guizhi decoction in the treatment of diseases may be related to the mechanism of biaxial regulation of body temperature and gastrointestinal motility, mucosal immune intervention, secretion of sweat glands, inflammation immune function and myocardial protective effect and so on.