1.
Indian Pediatr
;
2016 Nov; 53(11): 1019-1021
Artigo
em Inglês
| IMSEAR
| ID: sea-179343
RESUMO
Background: Neonatal purpura fulminans due to congenital protein C deficiency is a rare disorder. Case characteristics: A four-day-old neonate presented with multiple necrotic skin lesions with abnormal coagulation profile. Intervention and outcome: Skin lesions responded to repeated plasma transfusions but the neonate developed bilateral retinal detachment. A novel homozygous PROC gene mutation was noted in the neonate. Message: Molecular diagnosis and prenatal counseling in neonatal purpura fulminans are vital considering the poor outcome.