RESUMO
This paper focused on 3 rare lesions of breast - an exceedingly rare case of fibrocystic disease of breast with predominantly chondroid metaplasia. Giant lipoma of breast which is infrequently observed because of rarity in size and location, with only very few case reports available in literature and fibroadenoma with atypical ductal hyperplasia(ADH) of breast which is an unusual finding in the adolescent or young adult female.
RESUMO
The authors propose a musculoskeletal (MSK) magnetic resonance imaging (MRI) protocol using selected sequences for common orthopaedic indications. Selected sequences allow optimal visualisation of the indicated pathology while screening for other common conditions. The authors emphasise the need for standard positioning of the patient and standard orientation of scan planes to facilitate comparison with follow-up scans.
RESUMO
An agent-based computer simulation of death by inheritable mutations in a changing environment shows a maximal population, or avoids extinction, at some intermediate mutation rate of the individuals. Our results indicate that death seems needed to allow for evolution of the fittest, as required by a changing environment.
Simulação computacional de agentes individuais que se reproduzem e morrem por acúmulo de mutações herdadas mostra um máximo da população ou evita extinção, para taxas de mutação intermediárias. Assim, as mortes parecem necessárias para a evolução dos mais adaptados a um ambiente mutante.
Assuntos
Feminino , Humanos , Masculino , Simulação por Computador , Modelos Genéticos , Mutação/genética , Dinâmica Populacional , Seleção Genética/genética , Genética Populacional , Método de Monte Carlo , Fenótipo , Densidade Demográfica , Característica Quantitativa HerdávelRESUMO
The sexual version of the Penna model of biological aging, simulated since 1996, is compared here with alternative forms of reproduction as well as with models not involving aging. In particular we want to check how sexual forms of life could have evolved and won over earlier asexual forms hundreds of million years ago. This computer model is based on the mutation-accumulation theory of aging, using bits-strings to represent the genome. Its population dynamics is studied by Monte Carlo methods