RESUMO
Benign oral fibrous histiocytoma is a rare lesion in the head and neck region. This tumor usually presents as a single nodular, painless mass which grows slowly and varies in size from 2-3 cm to over 10cm. Most patients are under 50 years of age and a history of trauma; chronic infection and sun exposure are reported. Case Report: In this paper a case of benign fibrous histiocytoma in the tongue of a 44-year-old man is reported. In microscopic view spindle cell Fascicules, along with infiltration of multinucleated giant cells was presented and for definitive diagnosis immunohistochemistry staining for SMA, Desmin, MSA, CD68 and CD34 was conducted. Microscopic feature of oral fibrous histiocytoma may be similar to some soft tissue tumors. Therefore, IHC is necessary for definite diagnosis