RESUMO
To study the co existence of Hodgkins lymphoma in sickle cell disease in a 10-year-old boy who is also a known case of sickle cell anaemia presented to out centre with symptoms of fever, weight loss. History of previous blood transfusions was given. On clinical examination, he was found to have pallor, generalised lymphadenopathy, splenomegaly. Complete blood picture revealed haemoglobin of 9 g/dl, white blood cell count of 12,000/cu mm, platelet count of 2 lakhs. Biopsy from the cervical lymph node revealed effacement of lymph nodal architecture with replacement by scattered atypical mononuclear and binucleate Reed–Sternberg cells with moderate cytoplasm, large vesicular nucleus and prominent eosinophilic nucleoli against a background of, mixed population of small lymphocytes, plasma cells and few eosinophils. Immuno histochemistry revealed positive expression of CD15, CD30, Pax-5 in the atypical cells and thus proved to be Hodgkins lymphoma.
RESUMO
Plants are the source of many biologically active products and nowadays they are of great interest to the pharmaceutical industry. The plant kingdom still holds many species of plants containing substances of medicinal value which have yet to be discovered. Another important aspect of interest in plant drug research is the new concept of "No Specifically Increased Resistance" [NSIR] of an animal to diseases attributes to other substances, besides the active principles responsible for specific biological activity. In this work, we studied different ash values of dried stem powders and wound healing activity [excision wound model] of stem juice of Musa paradisiaca Linn. [Musaceae]. Our study revealed that the stem juice of Musa paradisiaca Linn. has considerable wound healing activity when compared with the standard drug Nitrofurazone